#Elderly Dosage

[telospgx]

When it comes to senior care, personalized drug responses are more crucial than ever. Pharmacogenetics testing in Addison, Texas, plays a pivotal role in ensuring that medications are tailored to individual genetic profiles. This approach helps in identifying the most effective treatments and avoiding adverse drug reactions, which is particularly important for the elderly who often have complex medical needs. By integrating pharmacogenetics testing, healthcare providers can significantly enhance the quality of care for seniors.

[destielmemenews]

"The researchers have not tested the process on humans, and it’s not clear what dosage of dye or delivery method would be necessary. Human skin is about 10 times thicker than that of a mouse, according to the researchers.

“Looking forward, this technology could make veins more visible, easing … the procedure of drawing blood or administering fluids via a needle — especially for elderly patients with veins that are difficult to locate,” said senior author Guosong Hong, a Stanford assistant professor of materials science, via email.

“Moreover, this innovation could assist in the early detection of skin cancer, improve light penetration for deep tissue treatments like photodynamic and photothermal therapies, and make laser-based tattoo removal more straightforward.”"

source 1

source 2

source 3

[scientia-rex]

Good morning! I have a question. When I look up info about vitamin D, I come across many claims that people generally don't get enough of it. In a recent episode of Maintenance Phase, however, the hosts called it a "scam" or overblown, at least (I don't remember the exact wording). So, like, what's the deal with vitamin D? Do Americans get enough of it?

Probably, mostly. At the very least, people should be tested before starting repletion. It probably has a role in osteoporosis treatment and prevention, BUT how much to take and what form and when is HOTLY debated and frequently conclusions are changing.

Just to take you on a spin through the most recent Cochrane reviews (THESE ARE NOT SINGLE STUDIES, in case any of the research-naive out there want to get pissy about them; look up what a Cochrane review actually is before trying to shit on it; also note that I did NOT say this will cover every fucking person and every hypothetical they can come up with, jesus CHRIST):

No role for vitamin D in asthma

Insufficient evidence to recommend it in sickle cell

Raising vitamin D levels in cystic fibrosis patients is not beneficial

No evidence of benefit of vitamin D in MS

Supplementing vitamin D in pregnancy may have small benefits but also risk of harms

No clinically significant benefit from vitamin D supplementation in chronic pain

Insufficient data on vitamin D in inflammatory bowel disease, but no evidence of benefit

No evidence of benefit of vitamin D supplementation in liver disease

Vitamin D does not appear to prevent cancer in general population

No evidence for benefit in supplementation of vitamin D in premenopausal women to prevent bone density loss

Possible small mortality benefit of D3, but not D2, in elderly patients, but also increased risk of kidney stones and hypercalcemia

Vitamin D alone ineffective, but combined with calcium may be effective, in preventing bone fractures in older adults

Insufficient evidence for vitamin D improving COVID-19 outcomes

Now, vitamin D plus calcium in people who have post-menopausal bone density loss does seem to prevent fractures. This is why doctors routinely recommend it. However, dosage and formulation are still debated as data are insufficient, and uncertainty still large.

So, do you need to supplement? Probably not. There is some fairly weak evidence that vitamin D supplementation may help with depression, but I would argue that it's going to be most relevant in people with pre-existing deficiencies, which Medicare is just hellbent on not letting me test for anymore. They've narrowed the coverage codes for testing so now even know vitamin D deficiency isn't considered a good enough reason to test. So Medicare has very clearly decided it's not relevant, for whatever that's worth, I spit on their graves, etc. Of course, then you get into the question of what counts as a deficiency, which we also really don't know.

And to be clear, I wasn't looking through the Cochrane review results with an angle--those are most of the first page of search results on their site, with the only one skipped being similar to another one I mentioned, and I stopped when I got bored. These should not be paywalled, as I am not logged into anything and I can read it all, so try clicking the side menu on the right if you have trouble getting into the weeds.

If anything, running through this little exercise has made me less likely to recommend vitamin D supplementation, so do with that what you will.

[tetary]

Apply Nmn Resveratrol Uk Order To Gather All Vital Details

Day-to-day medication dosage involving nmn 2000mg is proven for you to drastically minimize body mass throughout middle-aged along with elderly overweight or obese older people, and also minimize full blood choleseterol levels along with diastolic blood pressure levels. NMN is regarded as safe and sound with the Food, mainly because it won't obstruct typically given treatments. Even so, it is far better to go through product brands meticulously considering that NMN may incorporate various other substances that may change prescription medication programs. People who need to recognize nmn complex, they're going to go here https://kekanaturals.co.uk/products/nmn-complex-2000mg .

[ryverbind]

Faceless Fixation (Sal Fisher): Cut Me, Hurt Me, Use Me [26.2]

Sal's Lore Part 3

------

TW: substance abuse/addiction, su!c!dal thoughts, and mentions of self harm

++++++++

Chains gripped him, held him down under a torrent of consistent, suffocating, and lethal waves of affliction. It was a plague that had been taking him over for decades now and he wondered how he hadn't become used to it after all this time.

Every time it started to get bad, he shattered under the weight of realizing 'again.' He was trapped again. A victim of his own torment. He tore himself down, stripped himself of dignity and of hope. 

This time, he didn't care where these abyssal waters dragged him.

Sal's rapidly deteriorating life was transforming into something monstrous and untamed. He no longer recognized himself when he looked into the mirror-- not that it mattered much in the first place. He hadn't recognized himself since he was five years old. 

He stared blankly at his ceiling. Counting the stained tiles and filing through arbitrary numbers and combinations in his head no longer aided as a distraction. The only savior in his life happened to be the one thing that would tear him down for good. 

When he tried it the first time, upped his daily dosage of anxiety medication to three pills rather than one, he was thrilled. Finally, a solution to his mental torture. He had fallen into a near drunken state, his head clouded with fog and for once, not so many worries captured him so devilishly. 

Since then, he had slipped into a hellish routine. Wake up in the late afternoon, take much more of his medication than he should have, then he'd nap for hours or dissociate beneath his duvet. What else could he do to occupy his miserable days? The woman who assaulted him was in prison, but she wouldn't remain there forever. She wouldn't be there for nearly long enough.

All Sal could do was painstakingly count down the days to her release-- when he was sober enough to do so, of course.

When he would regain a bit of his clarity come nightfall, when the moon and stars occupied his empty days, he would stream. It was never for long-- he couldn't bear to engage in something he couldn't find it in himself to love anymore. She had stripped him of the few things he had once adored.

His birthday was approaching. He would be twenty two. In his past years, he feared the fated day. What if everyone forgot about him? What if no one wished him a happy birthday? But this year, he didn't even consider that, nor did he care. So what if everyone forgot him? He was beginning to forget himself too.

Sal glanced to the side, the weight of his own head too much for him to carry with benzodiazepines coursing through his veins. His internal enemy had transformed into his friend-- the medication he cursed for so many years had become his safe haven. He beheld the bottle, wondering if he could turn the pills inside into an eternal bed for himself. He could rest. He could finally leave it all. 

All the elderly scholars claimed that Aphrodite had been the greatest temptation, but Sal had found a substance that topped the goddess in that department.

He didn't want to continue in a world where he wasn't even living. Why continue to suffer when everything could be silent forever? 

The monster that haunted Sal laughed at him, mocked him as it towered over his limp form on the bed. The wispy trails of its shadows slithered around Sal's body, only adding to the chains that stood out against the fresh cuts along his skin. Its wicked grin failed to strike fear in Sal's heart this time. He looked at the abomination he was destined to become and didn't cower. With each passing day, he assumed he wouldn't be alive long enough to see this empty shell of a creature he'd eventually turn into. The land-born leviathan that made his life into a laughing stock had nothing on him if he could end it before it began. 

Sal lazily glared at it-- at the imitation of himself-- while his hand stumbled around his dresser for the bottle of medication.

"Sal?" Three knocks sounded on his bedroom door, painfully echoing around the dark vignette of his drugged mind. The bottle clattered to the floor. "Wanna come out with me and Lisa for dinner tonight?"

It was his father. Sal bit down on his scarred, chapped lips as the hallucinations of his greatest fears, conjured up by his own mind, dissipated into nothingness. Gone like that, in the blink of an eye. He cursed the odds. How come he couldn't fight his own battles?

He swallowed against the dryness in his mouth, waiting for an excuse to come to him. "Not tonight, dad. I'm still feeling a little sick." He slurred, giving his father the usual excuse, claiming he was suffering with allergies.

A muffled, defeated sigh. Sal waited with bated breath for his father to leave. The sooner the better. He didn't want the man who raised him to see him like this. He didn't want anyone to see him this way, which is precisely why he only left the room in the dead of night and early hours of the morning.

"Son," the words were gentle, sad. "Talk to me, please. You've told me you're sick for months now. I know that's not it." 

Sal gulped over the lump that suddenly formed in his throat, cutting off his airways. Tears sprung to his eyes, but he stayed quiet.  

"Your friends say that they don't see you anymore. You don't answer their texts or calls. Hell, you don't even open your bedroom door for them." Henry's voice cracked, the sound causing Sal to launch into an upright position. His weak arms were barely able to catch his weight when the room began to spin around him.

Sal squeezed his eyes shut in an attempt to clear his head, to right himself. His dad was outside his door, close to tears. He hadn't seen his father cry since the passing of his mother.

And his friends. Every day, without fail, they would try. Ash messaged him at least three times a day, called a couple times. Larry, Neil, and Todd would knock on his bedroom door to check in once or twice each. He would ignore them or give excuses every single time. He knew he was letting them down, but in this state, he didn't want to see them. He didn't want to see anyone.

"We have Gizmo at the apartment." Fuck, Gizmo. Sal's little man. After the first few days of falling into himself, Sal started asking Larry to take care of his cat in his stead. He didn't have the strength to look at his boy knowing that the feline could sense his downward spiral. "He's been with us for a few weeks now. He misses you. We all miss you."

Sal dropped his face into his hands, his fingers quaking with the revelation his father had bestowed upon him. Leaving his friends and family behind was already one thing, but the cat who saved him? He felt terrible. The monstrous version of himself was right for cackling at him. Sal was a pathetic excuse of a human.

"And I just want you to know that I love you. You're my boy, Sal. I adore every bit of you and I desperately wish I could hold you in my arms again the way I did the day you were born. With your little hands and feet." Henry took a deep, shuddering breath. "You know, I'm proud of you. You're talented at so many things. You're polite, you're strong, you're kind. Despite all the obstacles, you've... you've pushed through it and you've become a wonderful man. I'm proud of you, and I'm proud to call myself your father."

Sal felt a sob working up his throat, his heart pounding inside his chest. He gripped the front of his shirt in weak hands, squeezing the fabric as the pain of causing his father so much anguish became too much to bear. 

Hot tears slipped down his cheeks and he sniffled, feeling attacked by the onslaught of guilt, of fear, of regret. He thought he had conquered these emotions, finally beaten them. It created a hole in his heart, forced a deep ache to surface in his chest. Everything his medicine was meant to do failed on him now as harsh pants wracked his body, his thoughts on a rampage and his body suffering the consequences of the abuse he put himself through. 

"Sal," his father's voice was a bit frantic now. Sal knew he could hear the breakdown he was tumbling into. "Please, buddy. Let's talk. Let me help you."

Sal rushed to stand, his legs too tired to support him. He stumbled to the wall, another agonized sob breaking past the barriers he thought he'd built up. His hands trembled against the white wallpaper and he used it to guide himself to his awaiting father. He needed to get to him, tell him he was sorry. Tell him he loved him, beg his father to forgive him.

He gasped for breath, his chest so tight and his mind so muddled with negativity that he couldn't take a full breath. He was slowly slipping beneath the waves, barely able to keep his head above water.

Sal didn't let the terror of leaving his emotions bare to his father stop him when his quivering hand finally wrapped around his doorknob, unlocking it the moment he realized he'd had it locked for two days now.

He ripped the door open, the wood slamming against his bedroom door viciously.

Henry stood past the threshold, his eyes red-rimmed and a lone tear running down his flushed cheek. Sal was sure he looked much worse than his father, especially when Henry's gaze softened into something somber, something far more heartbreaking than the word 'sad' could truly encompass.

Sal launched at his father, wrapping his arms around his waist and squeezing. Henry rubbed his hands up and down Sal's back, trying to soothe him, comfort him in the only way he possibly could.

"I'm sorry," Sal cried, his tears wetting the front of his father's shirt, his shame leaking onto the solidity Henry brought him. "I'm so sorry."

The grief that overtook both Sal and his father weighed even more than the after effects of the drugs he had been abusing for so long. Burdened them more than the depression and pain that Sal had been suffocating with all this time. All of his problems were sharp pins and he was the voodoo doll. It all came back to drown him-- and now it was drowning the people he cared about most.

Sal spilled everything the moment he and Henry sank to the floor. He relived the exact moment he confessed what had happened to Ash just a few months ago. Once was enough, but twice couldn't be a coincidence. 

How many times was Sal going to blame his bad luck before he could finally see that he was the one tearing himself apart now?

On the floor, a heaping, sobbing mess before his father, Sal wondered how he'd be able to pick himself back up whenever his actions had thrown himself down this way. Henry tried to tell him he understood, that Sal was never to blame. That Sal never deserved all these things that happened to him. But Sal had resolved his mind to one thing-- falling apart in front of his father like this was something he never wanted to do again. Ignoring his friends and family, neglecting his Gizmo. They were all things he never, ever wanted to do again for as long as he lived. 

He didn't know if he'd get better, but the least he could do was try, right?

With Sal's permission and a conversation with Lisa, Henry helped in admitting Sal into a rehabilitation clinic.

It was the scariest and most revitalizing thing Sal had ever done for himself. Even if he wasn't sure about what he wanted from life anymore, it at least showed that some deep, hidden part of himself wanted to live. Maybe not for himself, but for those around him, at least.

Sal made some friends during the weeks that he spent away from streaming and away from the temptation of tearing himself apart. The first week and a half was miserable. He had to learn to survive without the help of more drugs than he needed. The dosage of his anxiety medicine was lowered to better accompany his journey toward healing. Worst of all were the constant headaches and nausea of withdrawal. Part of him believed his attempts to improve were in vain, especially during the sleepless nights where, sometimes, he could hear that monster clawing at his barred windows.

But, then the headaches began to go away. He was able to eat more than just crackers and soup once a day. He felt like going outside, walking around the garden that his clinic had. And, damn, he felt like talking when he and his hall-mates would meet with a counselor to discuss their day and their thoughts. 

Not being alone in his darkness inspired him. And that was when the writing began.

Sal's pen flew across the blank sheet of paper he had taken from the lounge down his hall. It hadn't been the first time he'd done this-- the past week, he had filled up a full stack of paper with words that came from the darkness that had tainted him for all these years. 

This paper, though. This one mattered the most.

He hardly had to think, his gaze flying across the page and his pencil scratching against the paper. It just came so easily to him.

"Preserve my youth Through words I write-- Forbidden truths Soaked with venom in the night.

Enslaved to my pen, Chained in this cage; Ink stains on my skin For my friends beyond the page.

Blood soaked rose thorns And bones for my quill-- Trapped in beauty that adorns The violence of a kill--"

Sal blinked when the paper slipped out from beneath his pencil, no doubt leaving a long, graphite mark across the page. 

He whipped his head to the side, looking at his roommate who pursed his lips at the paper. Sal relaxed a bit upon seeing him. He may have been Sal's roommate, but he'd also quickly become a friend. Quite a curious friend, at that.

Sal didn't know much about him, but the man encouraged his healing habits. That seemed like reason enough to consider him a friend.

His friend picked up another paper that lied on Sal's small desk on his side of the room. He glanced over it, his lips quirking up in a little smile. A smile that made Sal suddenly grow nervous. Poetry wasn't new to him, but he hadn't realized he had such an affinity for it until he'd come to rehab. His counselor had instructed his group to write a poem about their healing journey a week ago and Sal realized he'd loved the escape that came with it. It was about as freeing as playing his guitar, but much more creative and meaningful than the mediocre poetry he'd written before this.

Sal snapped himself out of the memory when his friend began reading the words on the page he'd just picked up. 

"Look at what I've become-- My mother's careful knitting is undone. Sixty stitches and a price never paid, Might as well have sliced me with a blade.

All gaping wounds and pity, Disgust has never looked so pretty. My own disgust or theirs;  Or is it just hospital rooms and wheelchairs?"

Sal snatched the paper back before his friend could read anymore. This one was personal and he didn't want all of his internalized anguish out in the open.

"That's enough," he rasped, tone quiet. 

His friend frowned. "It's good stuff, Sal. Don't be ashamed." Sal took a deep breath, trying to ignore the way the man's smooth, captivating voice seemed to lull him into feeling false confidence. And still, his friend continued. "Why don't you like people reading your work? You didn't read yours during the meeting the other day."

"It's embarrassing," Sal grumbled. He could feel his cheeks burning up beneath his prosthetic. "Give me the other."

His friend raised a defiant eyebrow.

Sal rolled his eyes as anxiety gripped him whole. He gestured to the paper and, through gritted teeth, forced out, "Please."

His friend grinned at him. "I'll give it back under one condition."

Sal sighed, beginning to grow frustrated, but he heard his friend out.

"Whatever the issue is, whether you're just shy or if you don't want people to see the scary parts of yourself, your poetry's good. That's undeniable." His friend's grin softened into a reassuring smile. "I have a band back home. We're just starting out. Why don't you write music for us? It would give us an excuse to be friends after all this."

Sal's lips parted in surprise. Write music for a band? He hadn't considered giving his poetry to anyone.

Sal's voice was hoarse as he managed to say, "I-- I don't know..." His poetry was his. He felt possessive of it-- he couldn't possibly let anyone else express his mind, even if it were through sound, could he?

His friend shrugged, handing his poetry back to him. "Think about it," he said to Sal. "No one has to know you write the lyrics. Might be a good way to express yourself and heal, you know? Music has been healing for me. Maybe it can do the same for you."

The man gave Sal a gentle smiled then walked out of their shared room. Sal watched him leave with ideas swirling around his head. 

Recently, he had begun to see a light at the end of the tunnel. Eating properly, going out into the sun, admiring the sunset, reading literature and poetry, writing poetry again, making friends... it had all begun to mold into this infectious hope. Something he thought he would never, ever feel. And now this opportunity to write music for a band... he felt like he was standing at the door that let in all the hope that swelled within him. He just had to choose how he would walk through that door and if he would take the offer his friend extended to him.

The tides had turned. Maybe music could be an escape for him again.

He thought about his friends proposition, considered his options, thought about all the other things he could do in his life. He thought about his friends back home, thought about his streaming career, other projects he'd been working on before things started to go downhill.

He made his decision, but he'd talk to his friend about that later.

Until then, he'd scratch away on his paper, pull the last broken bits of him out of his body and splatter it against the page.

------

A/N:::::::: i know this lore chapter isn't long, but the next one while be a little lengthier!! :3 i also think the next one will be the last for sal's lore as well.

as always, i'd like to address the heavy hitting topics included in this chapter. we've explored sal's suicidal thoughts before, so the main focus here is his addiction to his medication. As many of you know, there's been an opioid and drug epidemic in the US that has been around for over a decade now. many doctors abuse the option for medicine and prescribe it when it is not needed, or they prescribe much more than needed. of course, many people do need their medicines-- i'm one of them. the issue lies in the possible effects not being explored nearly enough. opioids, OTC's, and prescription medication can be very addictive due to the job that they do to regulate our system. it creates something of a euphoria or an escape when taken in excess and that's where the addiction can begin. while i'm not knowledgable enough on the topic to say much more about it, it is something i'd like to raise awareness about. addiction is heartbreaking, life-altering, and crippling. my father fell victim to addiction-- to the same type of medication that i've had Sal take in this chapter. it broke my family apart and it broke my dad. witnessing him slowly falling apart and being away from him during his time in rehab has completely altered the trajectory of my life. seeing his tears as he finally came to understand what had happened to him is genuinely some of the worst pain i think i've ever felt. i'm very happy to say that my family has been back together for a few years now and Father Ryver is doing so much better, but i can't say the same for other victims of addiction, especially considering that my aunt is going through the same thing right now.

remember that you are NEVER alone. i see you, i hear you, i love you. addiction is no one's fault, nor is it something to feel guilty over. it's a horrible thing that can happen during attempts at healing or completely unplanned, but it isn't forever. pain is temporary, love is forever.

if needed, i did some research on international hotlines as well as some in the US:

USA - Emergency Substance Abuse Hotline: 1-800-662-4357 EUROPE - Samaritans: 116 123                      Give Us A Shout: text SHOUT to 85258 AUSTRALIA - Sane Helpline: 1800 187 263 CANADA - Wellness Together (for mental health and substance abuse): 1-866-585-0445 or text WELLNESS to 741741 SOUTH AFRICA - Narcotics Anonymous: 0861 00 6962 NEW ZEALAND - Alcohol and Drug Helpline: 0800 787 797 PHILIPPINES - Substance Abuse Helpline: 1550 INDIA - National Toll Free Helpline: 1800-11-0031

anyway, as always, all my love to you darlings! stay true to yourself and stay strong. I LOVE YOU SO MUCH!! have a lovely morning, day, evening, night <333

[expertacademicassignmenthelp]

How Does The Drug Got Excreted / Eliminated From The Body?

Drug excretion is an important process in pharmacology, encompassing the elimination of pharmaceutical substances from the body. While the ultimate elimination of all drugs is inevitable, the specific pathways involved can vary significantly. Some drugs undergo extensive metabolic transformations before being excreted, while others are expelled from the body in their original form.

The kidneys play a central role in excreting water-soluble substances, effectively filtering them from the bloodstream. Meanwhile, the biliary system handles drugs that remain unabsorbed from the gastrointestinal tract, providing an alternative route for elimination. Although excretion through auxiliary channels such as the intestines, saliva, sweat, breast milk, and lungs is typically minimal, certain volatile anesthetics and residual drug traces in breast milk can have notable impacts, particularly on vulnerable populations such as infants.

Renal excretion constitutes a significant portion of drug elimination, accounting for approximately 20% of the plasma that is filtered through the glomeruli. While most water and electrolytes are reabsorbed back into circulation, polar compounds like drug metabolites are excreted predominantly in urine. However, it’s important to note that renal excretion tends to decrease with age, necessitating careful dosage adjustments for elderly patients to mitigate potential adverse effects.

Numerous factors influence the process of renal excretion, including the extent of protein binding, the degree of drug ionization affecting reabsorption rates, fluctuations in urine pH that can alter excretion dynamics, and the impact of metabolic inhibitors on tubular secretion mechanisms.

Biliary elimination, on the other hand, occurs when drugs traverse the biliary epithelium via active transport mechanisms. However, this process is not without limitations, as transporter saturation can impose constraints on drug excretion rates. Typically, larger molecules containing polar and lipophilic groups are excreted through bile, while smaller molecules tend to favor renal elimination pathways.

In addition to renal and biliary routes, drugs may also be eliminated to varying extents through auxiliary pathways such as saliva, tears, feces, sweat, and exhalation. While the quantities eliminated through these routes are generally minimal, drug excretion in breast milk can pose significant concerns for lactating mothers, potentially exposing nursing infants to pharmacological agents.

Understanding the pharmacokinetic parameters governing drug excretion is paramount for optimizing therapeutic regimens and minimizing the risk of adverse effects. Key parameters include the rate of elimination, clearance, elimination rate constant, and biologic half-life for drugs undergoing first-order elimination kinetics.

In conclusion, drug excretion represents a broad process influenced by a myriad of factors, necessitating comprehensive consideration to ensure the safe and efficacious use of pharmacotherapy.

For medical students navigating the complexities of their studies, Expert Academic Assignment Help serves as a beacon of professionalism and expertise. With a steadfast dedication to excellence and competency, our team provides invaluable support and guidance tailored to your academic needs. Do not hesitate to reach out to us for assistance on your academic journey, email: expertassignment46@gmail.com 

Your excellence our pride.

[ezzerzerah]

Hear me out. And sorry if this already exists but I haven't seen it and it's been running rampant circles in my head.

So you, the reader, were injured or something happened that put you in the hospital. The damage or after effects are enough to cause the need for a caretaker. However, since you're too poor to afford actual health care and you wouldn't dare bother friends and family with it. But you desperately need a caretaker or it's cup-o-ramen for the next several months.

You're offered an experimental program operated by none other than Fazbear Inc. It's a trial based program where they send out an animatronic to help bedridden or dependent customers with their day to day. You don't really need THAT much attention, but you still need help. And since it's still in experimental stages, it's free! And who are you to turn down a free program?

You sign up, and with surprisingly fast delivery (almost same day), you receive your very own Fazbear Inc. State-of-the-art caretaker bot! Complete with the ability to look after toddlers, teens, pets, adults, and even the elderly. Equipped with the sensors to detect many MANY kinds of sickness and disease, and can also discern different medicines and what dosages to use.

All caretaker animatronics are meant to be slightly different. Some look like bears, and others look like rabbits or chickens. But those felt all too cheesy for you, so you chose one that looked like the embodiment of the sun crossed with a jester. When you received your new robotic caretaker, you were quite surprised by how advanced the technology Faz Inc was playing with. The Sun Jester, you later learn his design name is just Sun, is quite lively. Offering actual conversation, and not just basic and boring conversation, but interesting and captivating conversation!

As the weeks go on, your meds start to have an effect on your sleep schedule, whether causing you to fall asleep late or causing you to stay up all night. One week, you had gotten a total of 12 minutes of sleep, you know, because Sun scanned you and freaked out. His sensors were sent into a frenzy, and he.. shut down? Went to sleep? You couldn't tell. But he was out for several hours (4-5 hours max). When he did wake up, his appearance shifted as well. His orange and yellow shades shifting to cooler blue and white-gray tones. The rays that Sun often spun around or retracted into his head were gone. His outfit remains the same, except now he adorns a sleeping cap as well, one much like the hat Santa wears. Although this one is blue with yellow stars and it has a bell inside the puffball.

---

Anyone interested? I've been thinking about writing a fic for it but idk TvT

Sorry if this makes no sense 😅

[desertowlet]

Marta Cabrera's good heart and kindness and attempts to making things right is just. breaks my heart and completely undoes me. the fact she still felt the need to help the very people who have done nothing but wrong her, who ignore her existence and only acknowledge her whenever was most convenient for them, and who tried to rob her of everything for the sole reason of serving themselves first and foremost. all the way to the point of telling her and saying she was not worthy of the very will Harlan himself wrote and insisting they were far more deserving of the inheritance of the very man they simply treated as an asset more than an actual family member. they used him at such an egregious degree, up until the point where he had to cut all of them off for their own good. yet somehow Marta, who has fostered a genuine and dear friendship with the elderly man she took good care of doesn't deserve this inheritance? she was far more deserving to attend Harlan Thrombey's funeral than his so-called family– the very family that did not even bother to invite her to said funeral. she was more family to Harlan Thrombey than anyone else in the entirety of the film and it shows with how he treats her– how much he cared about the well-being of Marta and her mother and sister, and making sure they were safe. Marta didn't even do any of this with the intention of getting a piece of the inheritance– she was just doing her job but so much more. she was an honest and kindhearted nurse who wanted to do the right thing for Harlan. she tried everything in her power to save his life once she realized she mixed up the dosages, and became inconsolable at the realization that she did not have the means to do that. Meanwhile Harlan's eldest grandson, his own flesh and blood, shamelessly plots and schemes his grandfather's murder in an act of cold vengeance when he realizes he can't have any share of the inheritance. Harlan may have cared about the Thrombeys and wanted to make things right before he passed, however there is a clear difference between them and Marta; she was Harlan's family.

[sowerbot]

Ok, so I officially started HRT one month ago, and I haven't been super public about that because I've just been enjoying the changes and was just focusing on logging them all and stuff, but now that I've settled in I'm stuck with a problem I didn't expect to have.

Too much darn time.

It felt like before, most of my time and energy was spent on being trans. Trying to find a clinic, researching dosages and elderly methods, working through my personal issues, accepting myself as a woman, Yada yada

But now I'm finally on estrogen and its like "what now?"

Theres nothing more for me to really do besides stay healthy so the hormones can do their thing, so now I have to figure out what I want to do with all this time and energy I have now.

I feel lucky, tho. Not many people get the chance to reinvent themselves like this.

Time for me to figure out what I like.

[shantitechnology]

The Benefits of Using Paracetamol Suppositories for Fever and Pain Management

Fever and pain are common health issues faced by individuals of all ages. While oral medications like tablets and syrups are widely used, they may not always be suitable for everyone, especially children, elderly individuals, or those with difficulty swallowing.  This is where Paracetamol suppositories come into play, offering an effective and practical alternative for managing fever and pain.

As a leading Paracetamol 500 mg suppository manufacturer, Centurion Healthcare Pvt. Ltd. ensures the availability of high-quality solutions to meet diverse healthcare needs.  This blog explores the numerous benefits of using Paracetamol suppositories and highlights their role in modern medicine.

What are Paracetamol Suppositories?

Paracetamol suppositories are solid, bullet-shaped medications inserted into the rectum, where they dissolve and are absorbed into the bloodstream.  These suppositories contain Paracetamol, a widely used analgesic and antipyretic agent known for its effectiveness in relieving pain and reducing fever.

Available in various dosages, including Paracetamol 500 mg, these suppositories are an excellent alternative for individuals who cannot take oral medications due to vomiting, nausea, or other issues.

Why Choose Paracetamol Suppositories?

Paracetamol suppositories are a versatile option for fever and pain management due to their unique mode of administration.  They are particularly beneficial in:

Pediatric Care:  Ideal for children who struggle with swallowing tablets or syrups.

Elderly Care:  Suitable for older adults who may have difficulty ingesting oral medications.

Post-Surgery Care:  Effective for patients unable to consume oral drugs due to surgery-related restrictions.

Emergency Use:  Useful when quick action is needed, such as during high fever or severe pain.

As a trusted Paracetamol 500 mg suppository supplier, Centurion Healthcare ensures that these products meet stringent quality standards, offering safe and effective solutions for healthcare providers and patients alike.

Key Benefits of Using Paracetamol Suppositories

1.         Convenient Administration

Paracetamol suppositories eliminate the need for swallowing pills or consuming liquids, making them convenient for individuals with swallowing difficulties or gastrointestinal issues.

This is particularly valuable in pediatric care, where administering oral medications can be challenging. Leading pharmaceutical companies in India, like Centurion Healthcare, focus on creating patient-friendly solutions to enhance treatment adherence.

2.         Rapid Absorption

Administered rectally, Paracetamol suppositories bypass the digestive system, allowing the medication to be absorbed directly into the bloodstream.  This leads to faster onset of action, providing quicker relief from fever and pain.

Centurion Healthcare, a Paracetamol 500 mg suppository exporter, ensures that its products are designed for optimal absorption, delivering reliable results across diverse patient groups.

3.         Reduced Gastrointestinal Irritation

Oral Paracetamol can sometimes cause gastrointestinal discomfort, especially in individuals with sensitive stomachs. Suppositories provide an excellent alternative, minimizing the risk of irritation or gastric side effects.

This makes Paracetamol suppositories a preferred choice for long-term pain management, as recommended by many healthcare professionals from top pharmaceutical companies in India.

4.         Suitable for Vomiting or Nausea

During episodes of vomiting or severe nausea, oral medications may not be retained in the stomach long enough to be effective.  Paracetamol suppositories overcome this limitation, ensuring consistent and reliable drug delivery.

Centurion Healthcare, recognized among the best pharmaceutical companies in India, specializes in manufacturing suppositories that address such challenges with precision and care.

5.         Precise Dosage

Suppositories are pre-measured, ensuring accurate dosing and reducing the risk of overdose.  This is particularly crucial for pediatric patients, where incorrect dosing can lead to adverse effects.

Centurion Healthcare, one of the top pharma companies in India, emphasizes precision and safety in every product, including Paracetamol suppositories.

Applications of Paracetamol Suppositories

Paracetamol suppositories are versatile and used in a variety of scenarios, such as:

Fever Management:  Ideal for managing high fever in children and adults.

Pain Relief:  Effective for mild to moderate pain, including headaches, muscle aches, and postoperative discomfort.

Chronic Conditions:  Useful in long-term pain management for conditions like arthritis.

Post-Surgical Recovery:  Provides relief without the need for oral administration, ensuring comfort during recovery.

As one of the best pharmaceutical companies in India, Centurion Healthcare delivers products that cater to these diverse applications, ensuring better patient outcomes.

Why Centurion Healthcare Pvt. Ltd.?

1.         Commitment to Quality

Centurion Healthcare is a prominent Paracetamol 500 mg suppository manufacturer, known for producing high-quality products that adhere to international standards.  Our manufacturing processes are certified, ensuring safety, efficacy, and reliability.

2.         Global Reach

As a trusted Paracetamol 500 mg suppository exporter, we supply our products to healthcare providers and distributors across the globe.  Our extensive network ensures timely delivery and unparalleled customer support.

3.         Focus on Innovation

Innovation is at the core of our operations.  As part of the best Indian pharma industry 2024, we continuously invest in research and development to create advanced healthcare solutions.

4.         Versatile Offerings

In addition to suppositories, we offer a wide range of pharmaceutical products, catering to diverse healthcare needs.  Recognized as one of the top pharmaceutical companies in India, we aim to make healthcare accessible and effective for all.

Centurion Healthcare:  A Leader in the Pharma Industry

Centurion Healthcare has cemented its position as one of the best pharmaceutical companies in India through a combination of quality, innovation, and customer-centricity.  With a focus on patient well-being, we strive to make a difference in global healthcare.

Part of the Best Pharmaceutical Industry in India

Our commitment to excellence has earned us a place among the best pharmaceutical industry in India.  From cutting-edge manufacturing facilities to rigorous quality control measures, we ensure our products meet the highest standards.

A Trusted Name among Pharma Manufacturing Companies in India

As one of the leading pharma manufacturing companies in India, Centurion Healthcare prioritizes the needs of patients and healthcare providers.  Our products are crafted with precision to address a wide range of medical conditions effectively.

The Future of Paracetamol Suppositories

The demand for Paracetamol suppositories is on the rise, driven by their effectiveness and versatility.  As healthcare providers and patients seek convenient and reliable options for fever and pain management, these products are expected to become a staple in modern medicine.

Centurion Healthcare, a leading Paracetamol 500 mg suppository supplier, is poised to meet this growing demand with innovative and high-quality solutions.

Conclusion

Paracetamol suppositories offer a convenient, effective, and safe alternative for managing fever and pain, especially in situations where oral medications are not suitable.  With benefits like rapid absorption, reduced gastrointestinal irritation, and precise dosing, they are an invaluable addition to modern healthcare.

As one of the best pharma companies in India, Centurion Healthcare Pvt. Ltd. takes pride in manufacturing and supplying premium Paracetamol suppositories that meet the diverse needs of patients worldwide.  Whether you are seeking a reliable Paracetamol 500 mg suppository exporter or a trusted partner from the best Indian pharma industry 2024, Centurion Healthcare is your go-to choice.

Partner with us and experience why we are among the top pharmaceutical companies in India and a leader in the best pharmaceutical industry in India.

[askthe-yellowcrown]

lady Heket?

I have…a question, something somewhat important.

I come from far, anchordeep to be specific..

..

….

The mushrooms..the ones that grow here…

*I paused pulling out a bag of assorted sized mushrooms..*

what are the medicinal uses for these? And what would be a proper dosage, I know that…using them can cause an odd reaction if using more than recommended..

*I poked the mushrooms around..*

would there be any way to use these to help elderly followers? Or followers with pain?

*I look up at her, kneeling being quiet and waiting patiently.*

-🐛💖

"they can work as painkillers, feed It to your followers and they will become numb. Or high. In any case It will probably make pain affect them less. I recommend one simple mushroom for just the less pain effect, up to four can brainwash them"

[kayvanh123]

Understanding Elderly Depression: Causes, Symptoms, and Treatment

As our population ages, understanding the mental health challenges faced by the elderly becomes increasingly important. Depression is a significant concern among older adults, affecting their overall well-being and quality of life. In this article, we will explore the causes, symptoms, and treatment options for elderly depression, providing valuable insights for caregivers, family members, and healthcare professionals.

What is Elderly Depression?

Elderly depression is a mental health disorder characterized by persistent sadness, loss of interest in activities, and a range of physical and emotional symptoms. It is not a normal part of aging but a medical condition that requires attention and treatment.

Causes of Depression in the Elderly

Physical Health Issues: Chronic illnesses such as heart disease, diabetes, and arthritis can contribute to depression. The physical pain and limitations these conditions impose can lead to feelings of hopelessness and despair.

Loss and Bereavement: The death of a spouse, friends, or family members can trigger profound grief and loneliness, increasing the risk of depression.

Social Isolation: Reduced social interactions due to retirement, mobility issues, or the loss of loved ones can lead to feelings of isolation and depression.

Medication Side Effects: Some medications commonly prescribed to older adults can have side effects that contribute to depressive symptoms.

Genetics: A family history of depression can increase the likelihood of developing the condition.

Life Transitions: Major life changes, such as moving to a nursing home or adjusting to a new living situation, can be stressful and contribute to depression.

Symptoms of Elderly Depression

Recognizing depression in the elderly can be challenging as symptoms may differ from those in younger individuals. Common symptoms include:

Persistent sadness or anxiety

Loss of interest in activities once enjoyed

Fatigue and lack of energy

Changes in appetite and weight

Difficulty sleeping or oversleeping

Feelings of worthlessness or guilt

Difficulty concentrating and making decisions

Physical symptoms such as aches and pains without a clear cause

Thoughts of death or suicide

Treatment Options for Elderly Depression

Psychotherapy: Cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT) are effective in treating depression by addressing negative thought patterns and improving coping strategies.

Medication: Antidepressants can be prescribed to help balance brain chemicals. It’s crucial to work closely with a healthcare provider to find the right medication and dosage, considering potential side effects and interactions with other medications.

Lifestyle Changes: Encouraging physical activity, a healthy diet, and regular sleep can improve mood and overall health.

Social Support: Maintaining strong social connections through family, friends, and community activities can help alleviate feelings of isolation and depression.

Support Groups: Joining a support group for older adults can provide a sense of belonging and understanding.

Medical Care: Managing chronic health conditions and ensuring proper medication management can reduce the physical factors contributing to depression.

Preventing Depression in the Elderly

Stay Connected: Encourage regular social interactions and participation in community activities.

Promote Physical Health: Encourage regular exercise and a balanced diet.

Provide Emotional Support: Be attentive and supportive, recognizing the emotional needs of older adults.

Monitor Medications: Be aware of potential side effects and interactions of prescribed medications.

Seek Professional Help: If signs of depression are present, seek the advice of healthcare professionals promptly.

Remember, if you need further guidance or support, don’t hesitate to reach out to your mental health professional or contact us for assistance.

[actualbird]

following on from your ask about luke and his illness, i was thinking about how he would be classed as chronically ill and would require immunizations and stuff that are given to kids/elderly/chronically ill like flu shots, covid boosters etc. what if luke hates having them?? like i don’t think he’s afraid of needles but im sure he hates the side effects of the jabs (like the stiff arm feeling!!). and then you mentioned that ideally w/ his chronic illness he would need many treatments and i fully imagine him texting the gc like “sorry im gonna be late to the nxx meeting my ecg appointment is DELAYED” or rushing in desperate for food because he had to starve himself for a test ;_; the chronic illness journey isn’t fun but it’s nice to know that luke would probably be in the trenches too

irt to my last ask on luke, how i'd write his treatment, and chronic illness

HES IN THE TRENCHES TOO YEAH!!!! and oh gosh i love these scenarios and hcs. it definitely isnt fun and it isnt a walk in the park but it slowly gets integrated into his life

an alarm on his phone for taking his meds on time, having to beg off of certain hangout plans because he has a doctor's appointment, having to get a whole bunch of shots constantly, fasting before bloodwork, being frustrated with treatment plan after treatment plan....

along the lines of treatment/diagnostic woes, i used to get 243987409328 EEGs back when i was getting my own neuro condition diagnosed (it never got diagnosed....) and i like to hc now that luke hates EEGs particularly because it's SO annoying and difficult to wash the gel node things (uhhh the sticky gel they use to stick the nodes on ur head? idk what it's called) off his scalp. it's also so difficult for him to fall asleep during the Fall Asleep portion of the test. his anti epileptics meds also mess with his mood when the dosage or type changes which is, you know, kinda hellis when hes already rather paranoid thanks to his secret agent background

just in general, luke has to go through A Lot, but god. he trucks through. because it's worth it.

[ill-caterpillar-7616]

My life is falling apart and I’m so close to a relapse

My marriage is crumbling due to my own mental health and lack of affection. I feel as though I’m failing my kid at every turn, even when everyone keeps saying I’m doing well or telling me how smart and well-behaved he is. I’ve had to move 2 hours away from my husband and toddler to my mom’s house as my grandmother is now needing 24/7 care probably until she passes (expected within a year but who fucking knows) since no one else in the family can or will be bothered by their own mother dying. An ACTUAL live in caregiver wouldn’t be covered by insurance and would be too expensive. My kid is going to have to live like we have split custody. I feel as though I have barely any true emotional support as my husband is struggling with his own battles that I’m trying so hard to fix/ help with since they’re mostly my fault. My friends are all long-distant or online, and I’m not REALLY that close to any of them at this point in my life. My mother is juggling her job, finances, her mother’s health, her mother’s impending death, another mouth to feed as I can’t bring much monetary assistance to the house, and so much more so it fucking seems like I can’t seem to even ask her to take my kid for 5 minutes after a LONG day, not only doing my duties to my kid and grandmother, but helping my own mother outside even though I have chronic joint pain and a fatigue condition that left me feeling like I was going to collapse from exhaustion, pain, and lack of oxygen by the time I finally pushed my body back inside. SHE WOULDNT EVEN LET ME GET THE QUESTION OUT OF MY MOUTH!! I had been struggling to get him to go to bed for over 30 minutes and I just needed a moment (we do NOT do the cry it out in this household). All I said was”Moma,-“ and it’s all “no, it’s not happening, I have to be up early,” as if I’m not having to ALSO wake up early to get my grandmother dressed, fed, taken to the bathroom, and received her toe fungal meds alongside the other laundry list of medications before she needs to be out the door at 8:30 in the morning

Now, I am aware of my responsibilities as a parent and that as I have MY child, he is MY responsibility, and I don’t want to push him off to other people who have enough on their plate, but to ask for 2 seconds of help from my own mother and to be shot down so quickly and (IMO) cruelly, fucking hurt. I’m taking care of her mother and so far, for just the price of a vape (I’m trying to quit. Also I don’t expect monetary return on help I’m just adding it in I guess. Idk at this point). I have a whole life and family that is falling apart but I know I’m the only option here. My siblings either work or are out of state. My aunts and uncles either have work (which some have the ability to still help even then), their own elderly to care for, or my favorite, care more about their weird church’s “volunteer work” or mowingg their lawn more than coming to help or even fucking visit. Like. Who fuxkin does that?!??!?

So with all of that info… I battled with an addiction to self harm for over 7 years. I’m riddled with scars on my body but I have been 4 years clean as of so far. However, with everything going on, it’s becoming harder and harder to push the thoughts away and think on the things that usually help me get away from those urges/temptations. I hate it because my husband and our baby have been the pillars to my continued clean streak/sobriety(?) and with everything falling apart as it is right now… I don’t know how much longer I can hold on to my sanity if I’m being honest. I have to cancel and put a rain check on both my therapy that I JUST FUCKING STARTED and my psychiatrist appointment (I hope I can just call him and let him know the dosage is fine). It’s all just a big fucking mess.

Im sorry. I know there are many details missing to all of this but it’s not for advice… I just needed to get it off my chest. I can’t tell anyone else. Can’t worry those who are my closest circle bc EVERYONE is dealing with something right now and my BS just …no.

[tiredtief]

AI is literally so fucking useless bro I was required to use Google's Gemini for a med school class exercise (to show how bad it is, actually) and it literally refused to generate a response for the first four times then gave me "if the doctor decides to lower the elderly patient's (medication) dosage, they will start by slowly reducing the dose" - no shit bro?? What's the point of using this to 'make life easier' if you need to overly simplify your prompt to even get a response then when you finally do get a response it's vastly inferior to just saying what you mean directly to the person you're talking to REEE

[dirtbag-linecook-kyloren]

1) You have no idea how excited I was when someone actually wanted to delve my AU list, and #16 is one I haven't really done any work on this one so I'm so happy to think more on it thank you so much @tinpotterror

2) au 16 is one I'm so excited to get a plot for I can't stress enough that I think this one is gonna be good I just don't have a main conflict yet but who knows maybe this post will brew it, I do some great thinking while typing shit

SO AU 16 is a hospital au

which yes yes I know

but I need you to imagine, to come along for the ride with me.

It's an emergency room, because it always is, that's how these things always go, and ben solo is nearing the end of his residency. four years of undergrad, four years of medical school, and he's ready to be a fully fledged doctor. It's all he's wanted for fuckin YEARS, and he's almost there.

But charge nurse Armitage Hux continues to be a pain in his ass. All he has are complaints; the way Ben charts, his patient demeanor, hell, he even questions the dosage on meds, sometimes. (And he's often right, though Ben will never admit it. 50mg ˆwouldˆ have killed that patient, he did mean 5mg.) Ben doesn't like it, but Hux spends a lot of time cleaning up his messes, to the point that Hux legit does not respect Ben. Literally calls him Ben, doesn't call him Dr. Anything, because he's inches away from being a nurse practitioner, and he's earned the right to feel that way.

My favorite game to play is how do I get snoke in this au, and I think snoke is an elderly patient who's a frequent flier. he's awful, he's cruel, and the only two people in the ED he likes are Hux and Ben, so they end up having to work together more than either would like, as Snoke's health declines. Does Ben try to ignore a DNR? maybe? does he terrorize the other nurses to the point that they refuse to do anything for him, and ben spends fifteen minutes on one poor teenage boys blood draw, because he's only found a vein like three times? definitely. Is there a mass casualty event, because those are always a plot point on hospital shows? it is now, and you'll never guess who wasn't working that day and comes in half delirious on a stretcher, because you guessed it itS HUX (coming back I've decided he was running a race and there was a shooting because I put plenty of my own nightmares into fan fiction and this would just be another.)

and ben obviously realizes in those moments, as he looks at hux in the hospital bed, heading into emergency surgery, how much he relies on that voice, how much he's been leaning on Hux's years more experience, how much he's been undervaluing that resource. And hux gets through surgery while Ben is having to help other patients and trying not to lose his mind, he gets admitted to a room and when he wakes up from anesthesia, who would happen to be sitting in his room, passed out after a 14 hour shift still in his scrubs but Ben solo, a cold cup of tea that was smuggled in sitting on his bedside table.

and Ben keeps visiting hux, although Hux doesn't know why. He assumes it's guilt, of some sort, and figures he can take advantage of it to get the good snacks from the vending machine, but he comes back to work and Ben is still nice? And at this point, it's getting confusing, but he just keeps letting it happen, because he's decided it's preferable to Ben from before, but in some ways, it's not, because he starts to miss some of the venom, and he can't figure out why, until he realizes that oh no he hates Ben but he was also 100% flirting and that's a terrible idea, they work together it would end so poorly

But ben won't stop looking at him with his big doe eyes and eventually hux breaks and kisses him, and ben's confused? and then hux is confused, because what was this all about if Ben didn't have a crush on him, but he flees the break room and goes home and ignores all the calls to his phone and shows up to his next shift and tries to pretend that nothing happened.

At which point another one of the nurses all but slaps ben over the head for being so dumb and then they bone i guess? I created most of this plot in the last five minutes so it needs some refinement but I just need one for the nurses tbh. THIS ONE IS FOR THE NURSES it's for every nurse that's ever been nice to me and also my friend tyra